Implications of species differences in assessing the toxicity of PVC combustion products and irritants such as HCL to humans

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The paper discusses the evaluations of the toxic effects of chemicals, which use animals as surrogates for man, and their effectiveness. A characterization of potential differences and similarities in toxicological response between rodents and man for PVC and HCL is contained, as well as considerable insight into the factors responsible for the differences regarding exposure and response.

SKU: P03960 Category: Tags: , , ,

Description

The paper discusses the evaluations of the toxic effects of chemicals, which use animals as surrogates for man, and their effectiveness. A characterization of potential differences and similarities in toxicological response between rodents and man for PVC and HCL is contained, as well as considerable insight into the factors responsible for the differences regarding exposure and response.

Additional information

Author(s)

Robert K. Hinderer, BFGoodrich Co., USA.

Publication/Event/Pages

Paper presented at WAI 59th Annual Convention, Atlanta, GA USA

Year

1989